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Sending Mail as a Domain Admin

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I migrated a company from Exchange 2003 to Exchange 2010.  Everything went well.  I have 2 individuals who have Domain Admin rights who have large (>10 GB each) email boxes and after an hour they are not able to send emails.  I know that Microsoft runs a program every hour that erases there send permission and I can go in and reset these but is there a work around so they can be Domain Admins and not get booted out of the "Manage Send As Permission" so they will be able to send and receive mail?  My exchange is running on a OS Server 2008 R2 non Domain Controller.  Thanks for any help.  I'm sure this has been asked but I can't find a work around on any forums.

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